Administration of an Autogenous Vaccine in Patients with Chronic Bacterial Osteomyelitis

Since we face the problem of rapidly growing rates of antimicrobial resistance, autovaccination may provide a treatment alternative at least in those patients which suffer from treatment refractory infections. Interest is turning towards the therapy of infectious diseases by stimulation of the immune defence mechanisms. In fact there are reports of drug resistance in a wide range of bacterial diseases. In our experience, autovaccine immunization has the potential to treat chronic infections such as osteomyelitis unresponsive to antimicrobial therapy.